This is a very common expression that means bored, tired. The literal translation is something like “my scrotum (or balls) is full of this”. It means you cannot take it anymore. Like when you are bored on a rainy day, watching a bad movie, or tired of working.
Used by both men and women.
- O Johnny não vem hoje de novo.
- Caralho! Estou de saco cheio dele e das faltas dele.